Survival-associated eQTLs across different cancer types
We identified 22,212 eQTLs associated with patient overall survival across different cancer types at FDR < 0.05.
|
Cancer type
|
SNP ID
|
SNP position (hg19)
|
Alleles (A/a)
|
log-rank test p-value
|
Sample size
|
Median survival time AA
|
Median survival time Aa
|
Median survival time aa
|
|
|---|---|---|---|---|---|---|---|---|---|
| COAD | rs76959049 | chr1:231958987 | A/C | 1.26E-5 | 263 | 20.13 | 10.55 | 3.1 | KM Plot |
| COAD | rs7703461 | chr5:75493412 | A/G | 1.13E-6 | 265 | 2.27 | 16.53 | 18.5 | KM Plot |
| COAD | rs77039815 | chr5:56258685 | G/GAT | 1.13E-6 | 262 | 19.3 | 15.85 | 5.2 | KM Plot |
| COAD | rs77089490 | chr6:128850674 | TAATA/T | 1.55E-6 | 257 | 18.07 | 16.37 | 5.73 | KM Plot |
| COAD | rs78167851 | chr5:56156455 | G/A | 1.14E-6 | 264 | 18.9 | 15.23 | 5.2 | KM Plot |
| COAD | rs79498944 | chr22:45903344 | C/G | 6.45E-14 | 255 | 18.9 | 16.37 | 1.08 | KM Plot |
| COAD | rs79683734 | chr5:56256606 | G/A | 1.18E-6 | 261 | 18.9 | 15.85 | 5.2 | KM Plot |
| COAD | rs80310300 | chr5:56215203 | G/A | 9.81E-7 | 264 | 19.3 | 14.6 | 5.2 | KM Plot |
| COAD | rs909693 | chr22:50556736 | G/A | 4.7E-14 | 265 | 17.45 | 19.52 | 3.07 | KM Plot |
| COAD | rs9997174 | chr4:10812968 | G/A | 0 | 257 | 19.7 | 16.47 | 0 | KM Plot |
| ESCA | rs1047302 | chr7:1098404 | C/T | 0.000102 | 141 | 5.13 | 8.83 | 3.72 | KM Plot |
| ESCA | rs10802467 | chr1:247251735 | G/A | 3.52E-5 | 142 | 6.77 | 11.52 | 3.87 | KM Plot |
| ESCA | rs10817477 | chr9:116075797 | A/G | 8.73E-7 | 142 | 7.13 | 8.4 | 0.1 | KM Plot |
| ESCA | rs11021370 | chr11:95726855 | C/T | 2.67E-6 | 142 | 1.4 | 6 | 7.25 | KM Plot |
| ESCA | rs114111237 | chr2:177487300 | T/C | 9.86E-13 | 140 | 5.75 | 13.4 | 0.8 | KM Plot |